The role of chemokines in ocular diseases. Part I. Structure and role of chemokines in chosen diseases
Malesińiski, R.; Mrugacz, M.łg.; Bakunowicz-Łazarczyk, A.
Klinika Oczna 109(7-9): 340-344
2007
ISSN/ISBN: 0023-2157 PMID: 18260294 Document Number: 614727
The chemokines are a large family of chemotactic cytokines produced by leucocytes, fibroblasts, keratynocytes and the others tissue cells. Chemokines stimulate and regulate leucocytes migration in inflammations. All the described human chemokines transmit intracellular signals by binding and activating specific G protein-coupled receptors on the cell surfaces of their target cells. Chemokines are involved in variety of inflammatory and autoimmune diseases.