Analysis of recurrence and prognosis after surgical resection for anorectal melanoma
Zhao, D-Bing.; Wu, Y-Kai.; Shao, Y-Fu.
Zhonghua Wei Chang Wai Ke Za Zhi 10(6): 540-542
2007
ISSN/ISBN: 1671-0274 PMID: 18000775 Document Number: 613807
To investigate the clinicopathologic factors related with recurrence and prognosis after surgical resection for anorectal melanoma. The clinicopathologic factors related to recurrence and prognosis of 50 patients with anorectal melanoma after surgical resection were retrospectively analyzed using univariate and multivariate methods. Forty-seven patients underwent radical operation, including 31 abdominoperineal resection (APR) and 16 sphincter preserving operation. The local recurrence rates were 16.1%(5/31) and 68.8%(11/16) respectively. chi(2) analysis revealed that operation pattern was associated with local recurrence rate. The 5-year survival rate was 18.2%. Univariate analysis revealed that single tumor, intramural infiltration and operation pattern were related with prognosis. Multivariate analysis revealed that intramural infiltration was the most important prognostic factor for anorectal melanoma. The prognosis of anorectal melanoma is poor. Early diagnosis and treatment are important for the improving of curative effect.