Analysis of the influence factors on the resection and prognosis of thymic tumors
Zhang, Z.Y.; Ren, H.; Yu, H.Q.
Zhonghua Zhong Liu Za Zhi 16(5): 375-378
1994
ISSN/ISBN: 0253-3766 PMID: 7895592 Document Number: 436138
One hundred eleven thymic tumors were intervened surgically, including 92 thymoma, 8 thymic carcinoid, and 10 thymic carcinoma. In this series 50.9% of the cases were complicated with various syndrome, 44.5% with myasthenia gravis (MG), more frequently in the epithelial cell type. Pure red cell aplasia often associated with the spindle-cell thymoma. Of the thymic carcinoid 50% had ectopic ACTH syndrome. Resection rate correlated with the size and invasion of the tumor. There were significant difference in resection rate among thymoma, thymic carcinoid, and thymic carcinoma. The degree of invasion undoubtedly influenced on resection. The 3-, 5-, and 10-year survival rates of the thymoma were 82.7%, 68.1% and 40.0% respectively. The prognosis depended on the pathological classification and the severity of neighbouring invasion, but MG had no significant effect on prognosis. Recurrence and metastasis of the tumor remained to be the main cause of late death.