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In vitro activity of ertapenem against staphylococci

Tuchiluş, C.; Goldu, I.; Poiata, A.

Revista Medico-Chirurgicala a Societatii de Medici Si Naturalisti Din Iasi 111(4): 1035-1039

2007

ISSN/ISBN: 0048-7848
PMID: 18389801
Document Number: 612185
Ertapenem is a new carbapenem with an excellent activity against different Gram-negative and Gram-positive bacteria. Its good antibacterial activity is closely related to high hydrolysis resistance by bacterial beta-lactamases. We evaluated antimicrobial activity of ertapenem by comparison that of methicillin, gatifloxacin, cefepime and linezolid against 455 staphylococci collected during 2006-2007 period from healthy individuals. Minimum inhibitory concentrations were determined by agar dilution technique. Ertapenem has an activity comparable to the other tested agents. Resistance rate was 1% for all investigated strains.

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