Indices of phagocytosis of staphylococci with different biological activity
Antonovskaia, I.I.; Anatoliĭ, S.A.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 3: 64-68
1976
ISSN/ISBN: 0372-9311 PMID: 961272 Document Number: 100506
An index of completion of phagocytosis was studied for staphylococcus cultures of various biological activity in experiments with surviving polymorphonuclear leukocytes. Among the coagulase-forming staphylococci virulent strains proved to be nonviable in a lesser percentage of cases than the avirulent ones. Coagulase- and mannite-negative cultures proved to be most unstable. Staphylococcus toxin depressed the migration of polymorphonuclear leukocytes to the focus of irritation, inhibited ingestion of the virulent, and, to a lesser degree, of avirulent coagulase-forming staphylococci, but failed to influence the ingestion of coagulase-negative epidermal staphylococci. The influence of staphylotoxin on the phagocytosis completion index was either the minimal or absent entirely.