Antiparasitic vaccines: where are we now?
Rogier, C.; Moukoko, C.E.E.; Orlandi-Pradines, E.; Briolant, S.éb.
La Revue du Praticien 57(2): 183-188
2007
ISSN/ISBN: 0035-2640 PMID: 17432523 Document Number: 610505
In more than one way, the development of antiparasitic vaccines is challenging, but major efforts have been made. A large number of clinical trials have been carried out and a few antigens have been tested in the endemic zone, especially against malaria. So far, no vaccine candidate has shown a sufficient and long-lasting effectiveness that would be useful for public health. However, the trials have shown without ambiguity that a certain level of clinical immunity against paludism, schistosomiasis or leishmaniasis could be induced by vaccination, in the experimental setting or in the field.