Spectroscopic study of hexahydroquinoline derivatives--a potential group of calcium antagonists

Mielcarek, J.; Simşek, R.; Safak, C.; Stefaniak, H.

Acta Poloniae Pharmaceutica 64(6): 487-490

2007


ISSN/ISBN: 0001-6837
PMID: 18323240
Document Number: 608850
Spectral properties of 2, 6, 6-trimethyl-3-carbmethoxy-4-phenyl-5-oxo -1,4,5,6,7,8-hexahydroquinoline derivatives (HHQ) with different substituents in the phenyl ring (-Cl, -NO2, -CF3, -CH3, -OCH3) have been studied. Their emission and absorption spectra have been analyzed and quantum yields of emission were determined. The quantum yield of emission was found to depend on the kind, number, and position of substituents in the phenyl ring: it was the highest for the chlorine derivatives of HHQ, and the lowest for the compounds containing -NO2 group.

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