Ten-year survival of patients with hepatocellular carcinoma after hepatectomy
Hashimoto, K.; Ikeda, Y.; Korenaga, D.; Tanoue, K.; Hamatake, M.; Kawasaki, K.; Yamaoka, T.; Iwatani, Y.; Takenaka, K.
Hepato-Gastroenterology 54(73): 163-166
2007
ISSN/ISBN: 0172-6390 PMID: 17419253 Document Number: 606728
Background/Aims: The characteristics in patients with hepatocellular carcinoma who survive more than 10 years after hepatectomy remain unclear.Methodology: Eighty-five cases of hepatocellular carcinoma were retrospectively identified as short-term survivors (S-group: < 5 years, n = 41), mediumterm survivors (M-group: >= 5 and < 10 years, n = 25), and long-term survivors (L-group: >= 10 years, n = 19) to examine the clinicopathologic factors for the 10-year survival after curative hepatectomy.Results: In the L-group, platelet count and albumin level were higher and total bilirubin level was lower than those in the S-group. In the S-group, the total bilirubin level was higher and vascular invasion was more frequent than those in the M-group. Multiple regression analysis revealed that only host-related factors such as age, albumin level, and total bilirubin level were selected as significant factors to determine the 10-year survival. However, no tumor-related factor was selected.Conclusions: The present study suggests that the important factor linked to the 10-year survival of hepatocellular carcinoma patients is the host-related factor, but not the tumor-related factor. Especially, younger age, higher albumin level, and lower total bilirubin level are quite important to determine the 10-year survival.