Oral histoplasmosis as the initial indication of HIV infection: a case report
White, J.; Khammissa, R.; Wood, N.H.; Meyerov, R.; Lemmer, J.; Feller, L.
Sadj Journal of the South African Dental Association 62(10): 452 454-5
2007
ISSN/ISBN: 1029-4864 PMID: 18500107 Document Number: 606701
Histoplasmosis is an opportunistic infection. In HIV-seropositive subjects, histoplasmosis tends to have a progressive and disseminated course. Oral lesions occur frequently and multiple sites within the mouth can be affected. Diagnosis of histoplasmosis is made by microscopic identification and culture of the fungus in material taken from the affected site. We present a case of oral histoplasmosis in which the mouth was the primary site of the fungal disease and this was the initial indicator of HIV infection. There were lesions of the gingivae and there was destruction of the hard palate with extension into the right maxillary sinus and the right nasal cavity.