Association of serum C-reactive protein and LDL:HDL with myocardial infarction
Kulsoom, B.; Nazrul, S.Hasnain.
Jpma. Journal of the Pakistan Medical Association 56(7): 318-322
2006
ISSN/ISBN: 0030-9982 PMID: 16900713 Document Number: 602440
To identify frequency of the following markers of atherosclerosis risk: high C-Reactive Protein (CRP) and ratio between serum levels of low density lipoprotein (LDL) and high density lipoprotein (HDL) and to determine the association of high serum CRP levels and LDL:HDL in the patients presenting at NICVD with first myocardial infarction. This case control study was conducted at National Institute for Cardiovascular Disease (NICVD), in Karachi, comprising of 50 male patients of acute myocardial infarction (without any other co-morbidity) and 50 matching controls. In this study, CRP levels were significantly high (p = 0.003) and serum HDL levels significantly low (p = 0.006) in patients as compared to controls. Serum LDL levels and the ratio of LDL and HDL were not significantly different among the two groups. High serum CRP levels rather than high LDL:HDL are associated with myocardial infarction in the patients presenting at NICVD with first myocardial infarction.