The relationship between high sensitivity C-reactive protein level at admission and myocardial perfusion after primary percutaneous intervention in patients with acute myocardial infarction
Zhang, Y-chen.; Jia, S-qing.; Wang, L.; Li, H-wei.
Zhonghua Xin Xue Guan Bing Za Zhi 34(5): 422-424
2006
ISSN/ISBN: 0253-3758 PMID: 16776956 Document Number: 605160
Objective This study was designed to investigate the relationship between high sensitivity C-reactive protein (hs-CRP) level at admission and myocardial perfusion after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction. Methods The study population consisted of 197 patients ( 154 men, mean age 60.94 +/- 11.62 years) who were admitted to our hospital with first acute myocardial infarction and underwent primary PCI in the infarct-related artery. Myocardial perfusion was evaluated by Thrombolysis In Myocardial Infarction (TIMI) myocardial perfusion grade (TMPG). Patients were divided into two groups according to TMPG after PCI. Group I consisted of 39 patients with TMPG 0-1 and group 2 consisted of 158 patients with TMPG 2-3. Serum hs-CRP levels at admission were measured. Results hs-CRP level at admission was significantly higher in group I than that in group 2 (P = 0.026). Conclusions Higher hs-CRP level at admission in patients with acute myocardial infarction is related to poorer myocardial perfusion post primary PCI.