The effect of actovegin on spermatogenesis in white male rats upon clinical death modeling
Shevantaeva, O.N.; Kosiuga, I.I.
Eksperimental'naia i Klinicheskaia Farmakologiia 69(2): 40-43
2006
ISSN/ISBN: 0869-2092 PMID: 16845939 Document Number: 601546
The indices of spermatogenesis in white male rats have been studied after clinical death modeling by means of cardiac fascicle compression. The model disorder leads to a reliable decrease in the number of spermatogenic epithelium, Sertoli cells, and Leydig cells in the testicles. A single injection of actovegin (10 mg/kg) during the reanimation period decreases the disturbances in spermatogenesis and leads to its complete recovery by the 45th day of postreanimation period.