Effect of 2,4-D ecotoxicants on spermatogenesis and fertility of albino rats

Galimov, S.N.; Valeeva, G.R.

Aviakosmicheskaia i Ekologicheskaia Meditsina 33(1): 32-34

1999


ISSN/ISBN: 0233-528X
PMID: 10330569
Document Number: 501983
Characteristics of spermatogenesis, morphometric changes in the Leydig's and Sertoli's cells, and fertility of albino rats exposed to various doses of 2.4-D were investigated. Chronic injection of the herbicide led to transitional sterility against pronounced disorders of spermatogenesis, hyperplasia of sertolicytes and predominance of low-active forms of the Leydig's cells. An assumption concerning possible role of altered gonadostat in genesis of the reproductive disorders is offered.

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