Assessment of the results of determination of the blood level of dehydroepiandrosterone sulfate by using various commercial reagents
Suplotov, S.N.; Khramov, E.B.; Iuzhakova, N.Iu.; Makarova, O.B.; Aksenova, N.V.
Klinicheskaia Laboratornaia Diagnostika 2006(11): 19-21
2006
ISSN/ISBN: 0869-2084 PMID: 17186777 Document Number: 600944
The results of determination of the blood levels of dehydroepiandrosterone (DHEA) sulfate (DHEA-S) were comparatively assessed, by Using the test systems "Steroid-IEA-DHEA-sulfate" (ZAO "Alkor Bio" (Saint Petersburg, Russia)) and "DHEA-S ELISA ("DRG Instruments GmbH (Germany)). The Studies were conducted in apparently healthy 19-59-year-old women living in the middle belt of Western Siberia. They revealed the high sensitivity of the study test systems to age-related changes in the blood concentration of DHEA-S. The normal blood DHEA-S concentrations levels given in the instruction to the "DHEA-S ELISA" test systems were found to be decreased in they are used to measure the content of the above analyzed parameter in women aged 19-39 years.