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Sepsis following transrectal prostate biopsy: a report of 2 cases and reviewed similar cases in Japan

Hoshi, A.; Nitta, M.; Hongoh, S.; Hanai, K.; Nishikawa, Z.; Kobayashi, Y.; Shima, M.; Hanai, T.; Hyochi, N.; Usui, Y.; Miyakita, H.; Terachi, T.

Hinyokika Kiyo. Acta Urologica Japonica 52(8): 645-649

2006

ISSN/ISBN: 0018-1994
PMID: 16972630
Document Number: 600713
We report two cases of sepsis and disseminated intravascular coagulation (DIC), potentially fatal complications, following transrectal prostate biopsy. We also review similar cases reported in Japan. Case 1: A 63-year-old man received a cathartic and levofloxacin (LVFX) for prophylaxis. After transrectal prostate biopsy, he presented with fever and chills. Blood cultures grew Escherichia coli resistant to LVFX. Under a diagnosis of sepsis, he received intensive management that included endotoxin removal therapy. The patient was hospitalized for 27 days. Case 2: A 64-year-old man received a cathartic and cefazolin (CEZ) for prophylaxis. He presented with fever and chills after biopsy, and was admitted to hospital. Blood cultures grew E. coli resistant to CEZ. Under a diagnosis of sepsis, he received intravenous antibiotics, transfusion, and anti-DIC drugs. The patient was hospitalized for 11 days.

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