Congenital hypopituitarism in agenesis of the anterior pituitary gland: immediate management and follow-up
Mussa, A.; Porta, F.; Baldassarre, G.; Corrias, A.; Bellone, J.; de Sanctis, C.
Minerva Pediatrica 58(4): 385-389
2006
ISSN/ISBN: 0026-4946 PMID: 17008848 Document Number: 598752
We report a case of an infant admitted to our division at 50 days of age, who presented acute abdomen, respiratory insufficiency, skeletal abnormalities, craniofacial dismorphism, low gain of weight. Despite negative at neonatal screening for hypothyroidism, laboratory analyses showed marked decrease of all pituitary hormones but ACTH, and low levels of cortisol. Magnetic resonance was indicative of adenohypophysis agenesis with maintained neurohypophysis. Results of substitutive therapy are reported.