Protein NMR-based screening in drug discovery
Zartler, E.R.; Shapiro, M.J.
Current Pharmaceutical Design 12(31): 3963-3972
2006
ISSN/ISBN: 1381-6128 PMID: 17100607 Document Number: 598308
Protein NMR as a screening tool in drug discovery has become prominent within the past ten years. Advances in protein manipulation, whether by biological means (labeling) or physical means (NMR), have created a powerful method that is able to observe ligand-target interactions in solution.
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