Constituents in the alkaloid fraction of Kushen decoction
Liu, B.; Shi, R.-B.
Zhongguo Zhong Yao Za Zhi 31(7): 557-560
2006
ISSN/ISBN: 1001-5302 PMID: 16780157 Document Number: 597573
To study the chemical constituents of the alkaloid fraction of Kushen decoction. Constituents were isolated by different kinds of column chromatography and their structures were elucidated with spectral methods. Eight compounds were isolated and identified as matrine (I), sophoridine (II), sophocarpine (III), sophoramine (IV), oxymatrine (V), oxysophocarpine (VI), aloperine (VII) and sparteine (VIII). All these compounds were isolated from Kushen decoction for the first time. Aloperine was found firstly in Sophora flavescens, or Scutellaria baicalensis, or Rehmannia glutinosa which constituted Kushen decoction.