Study on quality control of effective fraction in qixue bingzhi decoction
Huang, Z.-F.; Luan, L.-J.; Shao, Q.; Cheng, Y.-Y.
Zhongguo Zhong Yao Za Zhi 30(8): 580-583
2005
ISSN/ISBN: 1001-5302 PMID: 16011278 Document Number: 590724
To develop a method for quality control of effective fraction in Qi-Xue-Bing-Zhi decoction, a traditional Chinese medicine (TCM). PF samples, effective fraction from Qi-Xue-Bing-Zhi decoction, were used as example, and a HPLC assay for chemical fingerprint and quantitative analysis was established. The contents range of Paeoniflorin (PE), Naringin (NG) and Neohesperidin (NH) in effective fractions were changed from 12.5%-16.0%, 8.4%-12.4%, 12.8%-15.3%, and their average contents were (14.7 +/- 1.1)%, (10.6 +/- 1.2)%, (14.2 +/- 0.8)% (n = 10), respectively. The fingerprints of PF samples showed 25 common peaks, and the fingerprint similarity for PF samples were all above 99.00% by comparing with the standard chromatogram. The method reported could be used effectively for the quality control of effective fraction from TCM.