The peculiarities of serum levels of S100b protein and antibodies to it in patients with crisis and stable essential hypertension

Shirokov, E.A.; Gruden', M.A.; Denishchuk, I.S.; Elistratova, E.I.; Iurasov, V.V.; Iakovleva, N.K.; Shalavin, A.N.; Sherstnev, V.V.

Klinicheskaia Meditsina 84(11): 45-48

2006


ISSN/ISBN: 0023-2149
PMID: 17243610
Document Number: 597453
The article covers the results of research into the levels of S100b protein and antibodies to it in the serum of patients with crisis and stable essential hypertension. The results show that neutrophic protein dysmetabolism plays an important role in the pathogenesis of hypertonic dyscirculatory encephalopathy and the forming of cognitive disorder syndrome. The data obtained suggest that hypertensive crises lead to pathologic changes in hematoencephalic barrier permeability and the development of autoimmune reactions with participation of neutrophic proteins.

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