Determination of methamphetamine in whole blood by capillary zone electrophoresis after solid phase extraction
Gong, F.-J.; Zhang, R.-S.
Fa Yi Xue Za Zhi 22(5): 353-354
2006
ISSN/ISBN: 1004-5619 PMID: 17190148 Document Number: 597071
To develop a specific CZE method for the determination of methamphetamine in whole blood after solid phase extraction. With the doxapram as internal standard, Oasis column was used to extract drugs from whole blood and the sample was analysized by CZE. The method showed excellent linearity and the linear correlation coefficient was 0.994. The relative standard deviation for between-day and within-day were 5.31% and 2.22%, respectively. The method is effective, simple, reliable and has been used in the determination of methamphetamine in whole blood.