The impact of cigarette smoking on oocytes and embryos quality during in vitro fertilization program
Depa-Martynów, M.; Jedrzejczak, P.; Taszarek-Hauke, G.; Jósiak, M.; Pawelczyk, L.
Przeglad Lekarski 63(10): 838-840
2006
ISSN/ISBN: 0033-2240 PMID: 17288167 Document Number: 595476
The aim of the study was to investigate the influence of smoking on different parameters in woman treated by in vitro fertilization. Twenty-seven patients undergoing IVF were classified as smokers and 32 as non-smokers on the basis of medical history. Smokers had decreased number of retrieved oocytes compared with non-smokers (p < 0.05). Our study demonstrates that active cigarette smoking increases the zona pellucida thickness of oocytes and decreases a quality of oocytes. Cigarette smoking is associated with reduced number of embryo obtaining after classical in vitro fertilization in smokers compared to non-smokers, There was no significant difference in number embryos obtained after ICSI treatment in both groups. Women who smoked had also statistically significantly lower quality of embryos versus non-smokers patients. The clinical pregnancy rate per cycle in smokers was significantly lower.