A case of metastatic colon cancer treated with oxaliplatin combination chemotherapy
Tsujie, M.; Fujiwara, S.; Kida, H.; Hayashi, N.; Fukuchi, S.; Yoshida, T.; Ebisui, C.; Sakita, I.; Hasuike, Y.; Fujimoto, T.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 32(11): 1774-1775
2005
ISSN/ISBN: 0385-0684 PMID: 16315937 Document Number: 591889
A 77-year-old male had been operated for ascending colon cancer with liver metastases. After hepatic artery injection therapy and CPT-11 plus 5'-DFUR combination therapy, oxaliplatin-based systemic chemotherapy was performed. Consequently, the tumor size was controlled for about 10 months. During the chemotherapy, we observed grade 3 neurological toxicity, but not grade 3-4 blood toxicity. Thus, the QOL of the patient was properly maintained. We conclude that the oxaliplatin-based chemotherapy may be useful for patients suffering 5-FU and CPT-11 resistant metastatic colorectal cancer in Japan.
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