The thermodynamic stability of nanoconstructions based on the double-stranded DNA molecules
Zakharov, M.A.; Nechipurenko, I.D.; Lortkipanidze, G.B.; Evdokimov, I.M.
Biofizika 50(6): 1036-1041
2005
ISSN/ISBN: 0006-3029 PMID: 16358782 Document Number: 590998
The temperature stability of nanoconstructions formed by double-stranded DNA molecules fixed in the structure of their liquid crystalline dispersions and cross-linked by nanobridges was determined. It was shown that the heating of nanoconstructions is accompanied by a decrease in the amplitude of the negative bands in the CD spectrum both at lambda similar to 310 and lambda similar to 505 nm. Temperature "melting curves" were derived and characterzed by T-M values. The T-M values at lambda similar to 310 and lambda similar to 505 nm coincided with each other but differed from the T-M value characteristic of the DNA cholesteric liquid crystalline dispersion.