Coronary flow velocity reserve is diminished in hypertensive left ventricular hypertrophy
Nemes, A.; Neu, K.; Forster, T.; Kovacs, Z.; Csanady, M.
Kardiologia Polska 62(1): 1-5
2005
ISSN/ISBN: 0022-9032 PMID: 15815773 Document Number: 590808
Dipyridamole stress transesophageal echocardiography (STEE) is a feasible method for the evaluation of coronary flow velocity reserve (CFR). The aim of the present study was to investigate CFR in hypertensive patients with or without left ventricular hypertrophy (LVH). The study comprised 73 patients with a negative coronary angiogram (29 men and 44 women). Three different groups were compared: normotensive patients, hypertensive patients without LVH and hypertensive patients with LVH. CFR was significantly decreased in patients with hypertension with LVH as compared to normotensive cases (2.19+/-0.50 vs 2.71+/-1.10; p<0.05). CFR of hypertensive patients without LVH was only slightly reduced as compared to normotensive cases (2.44+/-0.81 vs 2.71+/-1.10; p=ns). In hypertensive patients with LVH, the LV mass and LV mass index were inversely related to CFR (r = -0.481 and -0.477, p<0.05, respectively). CFR is diminished in patients with hypertension. The degree of CFR reduction is related to the extent of LVH.