Left ventricular hypertrophy and arrhythmia. An aspect of hypertensive cardiomyopathy
Clémenty, J.; Dulhoste, M.N.; Coste, P.; Gil, A.
Archives des Maladies du Coeur et des Vaisseaux 84(Special Issue 3): 111-115
1991
ISSN/ISBN: 0003-9683 PMID: 1835364 Document Number: 381330
Epidemiological data has established a relationship between left ventricular hypertrophy (LVH) and sudden cardiac death. This relationship is independent. The search for ventricular and atrial arrhythmias in hypertensives confirms a greater prevalence of these arrhythmias in patients with LVH. The mechanism of these arrhythmias is multifactorial: ischemia, subendocardial fibrosis, increased sympathetic tone, electrolyte disturbances, age, and hemodynamic changes may be arrhythmogenic substrates both at the ventricular and auricular levels. The relationship between LVH (marker or cause) and the detected arrhythmias remain obscure. The most sensitive markers of severity seem to be the ECG parameters (LVH with overload), echocardiographic mass (greater than + 20%) and septal thickness (greater than 12 mm). The evolution of arrhythmias with regression of LVH is unknown. Respect of electrolyte equilibrium would seem to be the only unquestioned therapeutic intervention.