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Effects of mifepristone on the proliferation, apoptosis and cis-diamminedichloroplatinum sensitivity of cultured chemoresistant human ovarian cancer cells

Wang, G.; Shang, H-ling.; Xie, Y.; Xiao, P.; Li, X-jie.; Lin, T-cheng.; Li, G-yi.

Chinese Medical Journal 118(4): 333-336

2005

ISSN/ISBN: 0366-6999
PMID: 15740674
Document Number: 590465
Of late, more and more studies are being carried out to explore the anti-tumour activity of mifepristone. As Rose and Barnea1 reported, mifepristone can inhibit the growth of cultured ovarian carcinoma cells. The role of mifepristone in cis-diamminedichloroplatinum (CDDP) and taxol resistant ovarian carcinoma was found in Rocereto and colleagues' study.2 The purpose of this study was to examine the effect of mifepristone on the growth and CDDP-sensitivity of CDDP-resistant human ovarian carcinoma cells and give an experimental basis for the treatment with mifepristone of refractory ovarian carcinoma.

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Bao, L.; Wang, Y.; Ma, R.; Ren, X.; Cheng, R.; B, A. 2015: Apoptosis-inducing effects of lentinan on the proliferation of human bladder cancer T24 cells Pakistan Journal of Pharmaceutical Sciences 28(5): 1595-1600
Duraj, J.; Sedlak, J.; Bies, J.; Chovancova, J.; Chorvath, B. 2002: PSC 833 modulation of multidrug resistance to paclitaxel in cultured human ovarian carcinoma cells leads to apoptosis Anticancer Research 22(6a): 3425-3428
Cao, X.-W.; Fu, Z.-R.; Ding, G.-S. 2005: Effects of tacrolimus on proliferation, apoptosis, and fluorouracil sensitivity of liver cancer cell line of SMMC-7721 Hepatobiliary and Pancreatic Diseases International: Hbpd Int 4(2): 269-273
Gao, L.; Yang, J.-r.; Peng, Y.-y.; Pan, T.-j. 2011: Effects of staurosporine on the proliferation and apoptosis of prostate cancer PC-3 cells Zhonghua Nan Ke Xue 17(10): 884-887
Chen, C.D.; Dai, L.N.; Wang, M.; Lai, X.H.; Wang, J. 2017: Hypoxia induces autophagy in PA-l ovarian teratoma cells and resistance to growth inhibition and apoptosis by chemotherapeutic agent cis-diamminedichloroplatinum European Journal of Gynaecological Oncology 38(2): 277-281
Iwamoto, I.; Imada, A. 1992: Effects of growth factors on proliferation of cultured human peritoneal mesothelial cells Nihon Jinzo Gakkai Shi 34(11): 1201-1208
Zhang, W.; Li, Y.; Luo, J.; Zhao, X.; Xu, J.; Zhu, W.; Jiang, Y.; Fang, F. 2014: Proliferation inhibition and apoptosis induction of Juglone on human cervical cancer Caski cells Wei Sheng Yan Jiu 43(6): 959
Günthert, A.R.; Gründker, C.; Böttcher, B.; Emons, Günter. 2004: Luteinizing hormone-releasing hormone (LHRH) inhibits apoptosis induced by cytotoxic agent and UV-light but not apoptosis mediated through CD95 in human ovarian and endometrial cancer cells Anticancer Research 24(3a): 1727-1732
Wang, H.; Sun, B.; Zhang, Z.; Chen, J.; Hao, Q.; Sun, Y.; Yang, Y.; Wang, Z.; Pei, J. 2016: Effects of Acanthopanax senticosus polysaccharide on the proliferation, apoptosis and cell cycle in human HepG2 cells Die Pharmazie 71(4): 201-204
Guan, H-tao.; Xue, X-huan.; Wang, X-jing.; Li, A.; Qin, Z-yin. 2006: Effects of siRNA targeted to survivin in suppressing proliferation and inducing apoptosis in breast cancer MCF-7 cells Zhonghua Zhong Liu Za Zhi 28(5): 326-330
Hu, J.; Guo, Y.; Zhang, E.; Xu, W.; Shi, Y. 2009: Pressure mediated effects on proliferation, apoptosis and apoptosis-associated protein of endothelial cells in the flow field in vitro Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 26(4): 836-841
Andrews, P.A.; Albright, K.D. 1992: Mitochondrial defects in cis-diamminedichloroplatinum(II)-resistant human ovarian carcinoma cells Cancer Research 52(7): 1895-1901
Zhang, J.; Kan, Y.; Tian, Y.; Wang, Z.; Zhang, J. 2013: Effects of poly (ADP-ribosyl) polymerase (PARP) inhibitor on cisplatin resistance and proliferation of the ovarian cancer C13* cells Indian Journal of Medical Research 137(3): 527-532
Tang, D.G.; Li, L.; Chopra, D.P.; Porter, A.T. 1998: Extended survivability of prostate cancer cells in the absence of trophic factors: increased proliferation, evasion of apoptosis, and the role of apoptosis proteins Cancer Research 58(15): 3466-3479
Law, K.Seng.; Chen, H-Chang.; Liao, S-Kuei. 2007: Non-cytotoxic and sublethal paclitaxel treatment potentiates the sensitivity of cultured ovarian tumor SKOV-3 cells to lysis by lymphokine-activated killer cells Anticancer Research 27(2): 841-850
Frankel, A.; Buckman, R.; Kerbel, R.S. 1997: Abrogation of taxol-induced G2-M arrest and apoptosis in human ovarian cancer cells grown as multicellular tumor spheroids Cancer Research 57(12): 2388-2393
Liu, Y.-l.; Wang, Y.; Lang, Y.; Wu, X.-f.; Xiong, J.; Zhu, X.-h.; Zhang, Y.-h.; Zhang, S.-j.; Gong, L.-y.; Lu, Y.-p.; Ma, D. 2009: Inhibitory effects of an antisense PCDGF vector on proliferation and invasion of highly malignant ovarian cancer cells and the related mechanism Zhonghua Zhong Liu Za Zhi 31(2): 90-94
Mirkin, S.; Archer, D.F. 2004: Effects of mifepristone on vascular endothelial growth factor and thrombospondin-1 mRNA in Ishikawa cells: implication for the endometrial effects of mifepristone Contraception 70(4): 327-333
Yang, H.; He, Z.-q.; Zhao, Y.-x.; Wang, K.-w.; Zheng, D.; Su, Z.-l.; Tong, J.; Ma, J.; Wang, S.-j.; Xu, H.-x. 2011: Expression of TLR8 in human cervical cancer Hela cells and the effect of TLR8 agonist on the cell proliferation and apoptosis Zhonghua Zhong Liu Za Zhi 33(9): 643-648
Dunn, S.E.; Hardman, R.A.; Kari, F.W.; Barrett, J.C. 1997: Insulin-like growth factor 1 (IGF-1) alters drug sensitivity of HBL100 human breast cancer cells by inhibition of apoptosis induced by diverse anticancer drugs Cancer Research 57(13): 2687-2693