Laboratory study to investigate the efficacy of cyfluthrin EW treated nets against phlebotomine sandflies
Bongiorno, G.; Panchetti, F.; Zaim, M.; Maroli, M.
Annali Dell'istituto Superiore di Sanita 41(2): 247-252
2005
ISSN/ISBN: 0021-2571 PMID: 16244400 Document Number: 589994
The toxic and feeding inhibition effects of cyfluthrin-impregnated (CI) nets vs. deltamethrin-impregnated (DI) nets were assessed before/after 2 and 4 washes against Phlebotomus papatasi. CI nets (50, 25, and 12.5 mg active ingredient (a.i.)/m2) caused knock down and mortality rates of >90% (100% at the highest dose), while DI nets (25, 12.5, and 6.25 mg a.i./m2) showed low mortality rates (13.3-43.5%). Also, the after-washing activity of cyfluthrin (50 mg a.i./m2) was higher than deltamethrin (25 mg a.i./m2), with 24-h mortality of 66.7 and 48.9% for cyfluthrin, and 38.0 and 2.1% for deltamethrin, respectively after 2 and 4 washes. Before washing, cyfluthrin (50 mg a.i./m2) significantly prevented blood feeding, with respect to both untreated (88.6%) and DI nets (56.8%). Deltamethrin (25 mg a.i./m2) showed low feeding inhibition (48.4%), although it was significantly higher than control. Washing of CI nets (50 mg a.i./m2) decreased feeding inhibition by 26.6% and 41.3%, respectively after 2 and 4 washes. Two washes of DI nets (25 mg a.i./m2) led to high reduction in antifeeding inhibition (68.8%). These laboratory results, if confirmed by field evaluation, indicate cyfluthrin as a good candidate for the treatment of bed nets against phlebotomine sandflies.