Comparison of clinical efficacy between Huorongbushen and indomethacin in patients with oligospermia or asthenospermia
Sun, S.-P.; Shang, X.-J.; Huang, Y.-F.
Zhonghua Nan Ke Xue 11(8): 621-623
2005
ISSN/ISBN: 1009-3591 PMID: 16138585 Document Number: 589131
To compare the clinical efficacy and safety between Huorongbushen and indomethacin in patients with oligospermia or asthenospermia. 86 patients with oligoasthenospermia were received at our clinic of andrology. They were randomly divided into group A and B. The patients in group A received Huorongbushen 48 g daily for 3 months, and the other patients in group B were given indomethacin 50 mg daily for 3 months. The sperm parameters of the patients were analyzed by computer-assisted sperm analysis system before and after treatment. Patients of group A were significantly improved in sperm concentration, forward sperm motility, total sperm motility, straight line velocity and average path velocity. Patients of group B remained unimproved in sperm concentration and were significantly improved in other sperm parameters. The patients in group A reported a significantly higher sperm concentration than that in group B. There was no significant difference between group A and B in other sperm parameters. Compared with indomethacin, Huorongbushen is efficacious for oligoasthenospermia with lower side effects.