Rhinovirus diseases: pathogenesis, diagnostics and treatment
Faĭzuloev, E.B.; Nikonova, A.A.; Zverev, V.V.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 5: 115-121
2005
ISSN/ISBN: 0372-9311 PMID: 16279553 Document Number: 589023
Contemporary data on human rhinovirus diseases and their pathogenesis are presented. Special attention is paid to complications which may be caused by rhinovirus infections in allergy-susceptible patients. Furthermore, approaches to the diagnostics and treatment of rhinovirus diseases are described. In particular, the advantages of molecular methods for the diagnostics of rhinovirus infection (based on the PCR) in comparison with cultural and immunochemical methods are pointed out. New investigations aimed at the development of specific antirhinovirus preparations--capsid-binding (Pleconaril), blocking the binding of the virus with cell receptors (ICAM, soluble) and inhibiting rhinovirus protease 3C--have been considered.