Intestinal endotoxin in the pathogenesis of ocular inflammatory diseases and the antiendoxin constituent of its treatment
Vyshegurov, I.K.; Anikhovskaia, I.A.; Batmanov, I.E.; Iakovlev, M.I.
Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 1: 12-14
2007
ISSN/ISBN: 0031-2991 PMID: 17526210 Document Number: 609016
Blood was studied in 119 patients with ocular inflammatory lesions: endophthalmitis (n = 10), iridocyclitis of viral (n = 47) and unknown (n = 62) genesis, by using the procedures developed by the authors to determine the integral values of the concentration of endotoxin in systemic blood flow and the activity of antiendotoxin immunity. Intestinal endotoxin aggression was found to be involved in the pathogenesis of ocular inflammatory diseases. The use of drugs and procedures, which could diminish the entry of intestinal endotoxin into the blood stream and intensify the processes of its binding and release from systemic blood circulation, substantially enhanced the efficiency of a therapeutic process.