Thanatogenesis in poisoning with psychopharmaceuticals
Bogomolova, I.N.; Bogomolov, D.V.
Sudebno-Meditsinskaia Ekspertiza 48(2): 19-22
2005
ISSN/ISBN: 0039-4521 PMID: 15881137 Document Number: 588794
Discussed in the paper are thanatologically significant morphological signs in intoxication with some of psychic drugs. It was demonstrated that, in intoxication with azaleptin, phenazepam and aminazin, death comes mostly from affection of the brain including its edema and irreversible severe changes of neurons. In intoxication with tizercin, benzodiazepines and barbiturates, cardiac thanatogenesis as fibrillation of heart chambers combined with foci of myocytolysis. Sodium oxybutyrate brings about vascular collapse with subsequent development of fibrillation of heart chambers and of pulmonary edema. Intoxication with amitriptyline causes naturally necrotic nephrosis entailing uremic pneumonia and edema of the brain and heart.