Regulation of 3-desoxy-D-arabino-heptulosonate-7-phosphate synthetase in the bacteria Pseudomonas aurantiaca B-162
Feklistova, I.N.; Maksimova, N.P.
Molekuliarnaia Genetika Mikrobiologiia i Virusologiia 4: 34-36
2005
ISSN/ISBN: 0208-0613 PMID: 16334224 Document Number: 586349
The regulation of activity and synthesis of DAHP-synthase in Pseudomonas aurantiaca B-162 was studied. Analysis of partially purified preparations of the enzyme revealed two isoenzymes: DAHP-synthase is minor isoenzyme (sharing 22 % of enzyme activity) and is controlled by phenylalanine. In this case, 50% of inhibition of activity is possible by adding 5,5 10(-6) M of corresponding amino acid. Synthesis of DAHP-synthase is constitutive.