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Fibrinolytic activity of bacteria from Pseudomonas genus

Imshenetskiĭ, A.A.; Demina, N.S.; Lysenko, S.V.; Evdokimova, M.D.

Prikladnaia Biokhimiia i Mikrobiologiia 27(6): 845-849

1991

ISSN/ISBN: 0555-1099
PMID: 1839062
Document Number: 373370
A strain of the genera Pseudomonas genera was found to possess hemolytic, fibrinolytic and thrombolytic activities. The fibrinolytic activity of the lyophilized unpurified preparation was 900 conventional units/mg. After incubation in the blood plasma, the activity completely remained. The preparation (1 microgram/ml, 750 micrograms of protein) obtained by precipitation with ammonium sulfate (80% saturation) completely lysed in vitro human blood thrombi for 50 min. The strain studied can find practical applications in medical industry.

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