Growth hormone deficiency in children and adults
Krysiak, R.; Okopień, B.ła.; Herman, Z.S.ła.
Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego 19(113): 704-709
2005
ISSN/ISBN: 1426-9686 PMID: 16498817 Document Number: 585756
Recently, it has become clear that growth hormone (GH) deficiency is by far more frequent disease than it was previously thought. This disorder, associated with remarkable morbidity and mortality, is characterised by a variety of auxological, clinical, genetic, radiological and laboratory abnomalities, which may be pronounced to a different extent in patients. Despite progress made in its recognition and treatment, diagnosis of GH deficiency is still the subject of many debates and controversies. Numerous studies have helped to determine the optimum management of GH replacement in both children and adults. In this paper, aetiology, symptoms, diagnosis and treatment of GH deficiency in various age groups are reviewed with putting special emphasis on the results of recently published studies.