Hemolytic uremic syndrome associated with invasive Streptococcus pneumoniae infection: report of one case
Ou, C-Yen.; Chiou, Y-Hsuan.; Chang, J-Tzong.; Chiu, C-Lan.; Shih, C-Hung.; Hsieh, K-Sheng.
Acta Paediatrica Taiwanica 46(6): 381-384
2005
ISSN/ISBN: 1608-8115 PMID: 16640042 Document Number: 584809
Hemolytic uremic syndrome (HUS) most commonly follows an episode of gastroenteritis associated with Escherichia coli (O157:H7). S. pneumoniae-associated HUS is rare and has been reported having a high morbidity and mortality rate. We present a 1-year-5-month-old girl who developed S. pneumoniae-associated HUS and positive T-activation testing. She received antibiotics, washed red blood cell transfusion and early continuous venovenous hemodiafiltration treatment. She had chronic renal failure but was without other sequelae after 8 months, follow-up. Early dialysis intervention in S. pneumoiae-induced HUS patients decreasing the morbidity and mortality rate is discussed, and the literature is reviewed.