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Effect of a levopromazine-thymalin combination on the development of toxic edema and swelling in the brain

Platonov, I.A.; Vonogel', V.G.; Andreeva, T.A.

Eksperimental'naia i Klinicheskaia Farmakologiia 67(1): 48-50

2004

ISSN/ISBN: 0869-2092
PMID: 15079910
Document Number: 583464
The development of toxic edematous brain swelling in rats is accompanied by disproteinemia of the blood plasma and buildup of the gamma-globulin fraction. The administration of levopromazine (5 mg/kg), thymalin (1.2 mg/kg), or their combination reduces this disorder in the blood protein fractions. The antiedematous effect of the levopromazine--thymalin combination has an additive synergistic interaction.

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