The effect of fenibut on the ultrastructure of the brain mitochondria in traumatic edema and swelling
Novikov, V.E.; Naperstnikov, V.V.
Eksperimental'naia i Klinicheskaia Farmakologiia 57(2): 13-16
1994
ISSN/ISBN: 0869-2092 PMID: 8205040 Document Number: 422840
Rat experiments using electron microscopy have established that profound destructive changes occur in the mitochondria in the intra- and perifocal traumatic area in dynamics of traumatic edema-swelling. With phenibut, 50 mg/kg, there is an increase in the number of mitochondria in the brain tissue of the perifocal area, their destructive changes are less pronounced. It is assumed that the positive effect of phenibut on brain bioenergetic processes in the posttraumatic period is associated with the changes.