Correction of acute psychotic states in schizophrenia by rispolept solution per os
Panteleeva, G.P.; Korenev, A.N.; Barkhatova, A.N.
Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova 104(12): 43-50
2004
ISSN/ISBN: 1997-7298 PMID: 15847326 Document Number: 570598
To stop acute psychotic states during the first episode or relapses of schizophrenia, 37 patients were treated with rispolept solution per os during 2 weeks. A procedure of a fast transition to optimal daily doses of the drug after 1 day of treatment (searching period) with a following stabilization of mean daily doses (5.02-5.7 mg) at the stage of 14 day treatment course was used. Positive therapeutic effect by PANSS total score reduction, along with minor side-effects, were found in 91.9% patients. Stopping effect of rispolept on acute psychotic states, emerging from day 1 of the treatment, and general antipsychotic and therapeutic action, beginning from day 2-3 and increasing to day 14, were stated out. Efficacy of the drug in syndromes differing by psychopathological structure is emphasized.