Valpromide (Depamide) in the treatment of acute psychotic states. Open clinical study
Altamura, A.C.; Basile, R.; Mauri, M.; Cazzullo, C.L.
Acta Psychiatrica Belgica 86(3): 297-304
1986
ISSN/ISBN: 0300-8967 PMID: 2875606 Document Number: 276111
In an open clinical study on the effect of Depamide in acute psychosis, 59 schizophrenic and 23 manic hospitalized patients were tested. They were divided in two groups: in group A, Depamide was administered only after an initial period of treatment with haloperidol or chlorpromazine; in group B instead, Depamide was added from the beginning of the neuroleptic treatment. The results show that the association of Depamide with neuroleptics leads to a reduction of agitation and of the hospitalization period, whereas it ameliorates the adaptation of the patients to the therapeutic milieu.