Immune response to vaccination by Grippol in female northerners from Arkhagel'sk
Shegoleva, L.S.; Zhilina, L.P.; Fardzinova, V.F.; Dobrodeeva, L.K.
Klinicheskaia Laboratornaia Diagnostika 2004(3): 43-46
2004
ISSN/ISBN: 0869-2084 PMID: 15137203 Document Number: 570346
The immune-system condition of virtually healthy subjects (aged 35-45) was studied before vaccination ("Grippol") and 1 week later. An intense formation of antibodies to virus hemagglutinin is associated with lymphoproliferative reaction combined with differentiation of immune-competent cells (ICC) and with a higher phagocyte activity. A lack of any changed reactions to the administered antigen is interrelated with a deficit of phagocyte protection and with an activated ICC apoptosis.
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