Features of tanatogenesis and extensiveness of myocardial infarction depending on severity of atherosclerotic stenosis of the coronary arteries
Nefedova, G.A.; Galankina, I.E.
Arkhiv Patologii 66(4): 17-20
2004
ISSN/ISBN: 0004-1955 PMID: 15449682 Document Number: 570018
142 fatal cases of acute myocardial infarction (AMI) are analyzed. In 56% cases the surface of AMI exceeded 50% of the working surface of the left ventricle and patients died, as a rule, during the first week of the disease of cardiogenic shock or progressing heart failure. In cases of a small AMI (up to 30% of working surface of the left ventricle, 25% cases) the frequent cause of death was external cardiorrhexis. It is emphasized that the size of AMI is not always determined by severity of stenosing atherosclerosis in the coronary arteries since isolated stenosis of one branch can also provoke a large AMI. The results are in favour of more active use of prophylactic surgical (including endovascular) treatment of ishemic heart disease before the development of a large AMI.