Isolation and structure identification of C-25 epimers of inokosterone from Achyranthes bidentata Blume
Zhu, T.-T.; Liang, H.; Zhao, Y.-Y.; Wang, B.
Yao Xue Xue Bao 39(11): 913-916
2004
ISSN/ISBN: 0513-4870 PMID: 15696932 Document Number: 569010
To isolate C-25 epimers of inokosterone from Achyranthes bidentata Blume. and identify their structures. To separate C-25 epimers of inokosterone by using various kinds of chromatography methods and identify their structures on basis of spectral analysis and chemical method. Three compounds were isolated and their structures were established as 25S-inokosterone (1), 25R-inokosterone (2) and ecdysterone (3). Compounds 1 and 2 are new C-25 configuration isomers from Achyranthes bidentata Blume., their absolute configurations are elucidated at the first time, and their 13CNMR data are reported for the first time.