Studies on crosslinkable coatings for biomedical application
Ji, J.; Chen, W.; Xu, J.; Shen, J.; Fang, D.; Sun, F.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 21(1): 122-125
2004
ISSN/ISBN: 1001-5515 PMID: 15022481 Document Number: 568488
A novel crosslinkable coating for biomedical device was prepared by copolymerization of the constituent monomers via a free radical method. 1H-NMR and IR results indicated it had desirable structure. Surface characterization revealed that surface reorganization occurred in aqueous environment and a polyethylene oxied (PEO) enrichment surface was developed on coated surface. The in-vitro platelet-adhesion test and the plasma recalcification time(PRT) determination showed that the coated surface could resist the blood coagulation effectively.