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Detection of differentially expressed genes in hepatocellularcarcinoma cells SMMC-7721 treated with Typhonium giganteum extract by mRNA differential display

Wang, S.-q.; Ni, H.; Cheng, H.; Wang, G.-l.; Wang, T.-s.; Chen, L.

Zhongguo Zhong Yao Za Zhi 29(10): 974-977

2004

ISSN/ISBN: 1001-5302
PMID: 15631087
Document Number: 567985
To screen and identify the differentially expressed genes in hepatocellular carcinoma cells SMMC-7721 responsing to the aqueous extract from dried powdered rhizomes of Typhonium giganteum (AEoTGE). The response of hepatocellular carcinoma cells SMMC-7721 to AEoTGE was explored with the technique of mRNA differential display. After hepatocarcinoma cells SMMC-7721 were treated by AEoTGE for 36 hours, 1 gene expression was upgrade and 1 gene expression was downgrade induced by AEoTGE. The research has provided important clues for the molecular mechanism of how hepatocarcinoma cells responseing to T. giganteum.

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