Clinical and laboratory evaluation of efficiency and tolerance of the "Nikavir" in acute hepatitis B
Cheshik, S.G.; Malinnikova, E.I.; Cheshik, D.S.; Malyshev, N.A.
Voprosy Virusologii 48(3): 40-44
2003
ISSN/ISBN: 0507-4088 PMID: 12894480 Document Number: 562252
New antiviral drug "Nikavir" was clinically tested in acute hepatitis B (AHB). A total of 60 AHB patients were followed up; 30 patients were in the main group and 30 persons were in the control group. The treatment with Nikavir of AHB patients was shown to ensure a favorable clinical disease course and it was accompanied by a quicker rate in reduction of the activity of serum enzymes AIAT, AcAT, alkaline phosphatase and of gamma-glutamil-transpeptidase; besides, it was accompanied by an early elimination of such serum markers of AHB like HBeAg, HbsAg and HBV DNA. Wikavir can be used in the treatment of patients with mild and moderate forms of AHB.