So-called "superficial" bladder tumors. which classification in 2003? Part 2: Flat urothelial lesions
Sibony, M.; Billerey, C.
Annales de Pathologie 23(1): 35-45
2003
ISSN/ISBN: 0242-6498 PMID: 12743498 Document Number: 560566
Flat urothelial lesions of the urinary bladder have been recently discussed by the International Society of Urological Pathology (ISUP) in 1998 and more recently redefined by an international consultation held in Ancona, Italy in 2001. This paper summarizes and illustrates the recent literature about non-papillary lesions of the urinary bladder. Flat urothelial lesions include: epithelial abnormalities (reactive urothelial atypia and flat hyperplasia), preneoplastic lesion (dysplasia) and neoplastic non invasive carcinoma (carcinoma in situ) and a new category of presumed neoplastic lesions and conditions; the latter points out to a notion of tumor biology, which may help to the understanding of urothelial carcinogenesis.