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Expression of allergens in E. coli and plants--benefits and drawbacks

Breiteneder, H.; Wagner, B.

Arbeiten aus dem Paul-Ehrlich-Institut Zu Frankfurt A.M 94: 178-187

2003

ISSN/ISBN: 0936-8671
PMID: 15119037
Document Number: 559607
Recombinant allergens are quickly becoming the reagents of choice for diagnosis and therapy of type I allergic diseases. Consequently, the different methods for the production of recombinant proteins that are available today are of great interest to allergologists. Without doubt, bacterial expression will continue to play a pivotal role. In addition, plant-based expression systems will be needed to overcome problems inherent in the E. coli systems and to allow the production of glycoallergens or allergens of more complex folding.

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