Non-metastatic intrahepatic cholestasis associated with bronchial adenocarcinoma
Saintigny, P.; Spano, J-Philippe.; Tcherakian, Fçoise.; Pailler, M-Christine.; Breau, J-Luc.
Annales de Medecine Interne 154(3): 171-175
2003
ISSN/ISBN: 0003-410X PMID: 12910044 Document Number: 559523
In 1961, Stauffer first described a syndrome characterized by nonmetastatic intrahepatic cholestasis associated with undifferentiated renal adenocarcinoma. Since that time, this syndrome has been associated with other tumor diseases. We describe here a patient with lung adenocarcinoma which led to paraneoplastic cholestasis. We discuss the diagnosis and review the literature, emphasizing the pathophysiology of Stauffer's syndrome.