Soft tissue sarcomas: research of prognostic factors and therapeutics scheme
Montagnese, A.; Sturla, M.; Bruno, I.; Bracaglia, R.; Salgarello, M.; Seccia, A.; Farallo, E.
Journal of Experimental and Clinical Cancer Research Cr 22(4 Suppl): 219-222
2003
ISSN/ISBN: 0392-9078 PMID: 16767935 Document Number: 559483
The Soft Tissue Sarcomas shows consisting mortality that grazes 50%. Commonly the histologic type, the largeness of the tumor and the degree of malignity, are considered prognostic factors influencing the survival of patients affected from such tumor. The aim of our study is to characterize the new prognostic factors influencing the local recidives and metastatic dissemination. We have analysed 17 possible clinical and histologic prognostic factors in 80 patients affected of soft tissue sarcomas. The results have dimonstrated that: the compartimentality and the cellular differentiation seem to be more influent to the insurgence of local recidives and metastasis; while the low malignity degree, the wide surgical margins and the histopatological characters of benignity can influense positively the survival.